Package: surrosurv Type: Package Title: Evaluation of Failure Time Surrogate Endpoints in Individual Patient Data Meta-Analyses Version: 1.1.27 Authors@R: c( person("Federico", "Rotolo", role="aut", email="federico.rotolo@gustaveroussy.fr", comment = c(ORCID = "0000-0003-4837-6501")), person("Xavier", "Paoletti", role="ctb"), person("Marc", "Buyse", role="ctb"), person("Tomasz", "Burzykowski", role="ctb"), person("Stefan", "Michiels", role="ctb", email="stefan.michiels@gustaveroussy.fr", comment = c(ORCID = "0000-0002-6963-2968")), person("Dan", "Chaltiel", role="cre", email="dan.chaltiel@gustaveroussy.fr", comment = c(ORCID = "0000-0003-3488-779X"))) Maintainer: Dan Chaltiel Description: Provides functions for the evaluation of surrogate endpoints when both the surrogate and the true endpoint are failure time variables. The approaches implemented are: (1) the two-step approach (Burzykowski et al, 2001) with a copula model (Clayton, Plackett, Hougaard) at the first step and either a linear regression of log-hazard ratios at the second step (either adjusted or not for measurement error); (2) mixed proportional hazard models estimated via mixed Poisson GLM (Rotolo et al, 2017 ). Depends: R (>= 3.5.0) Imports: copula, eha, grDevices, lme4, MASS, Matrix, msm, mvmeta, optimx, parallel, parfm, stats, survival License: GPL-2 URL: https://github.com/Oncostat/surrosurv BugReports: https://github.com/Oncostat/surrosurv/issues/ VignetteBuilder: R.rsp Suggests: R.rsp, testthat (>= 3.0.0) Encoding: UTF-8 Config/testthat/edition: 3 Config/pak/sysreqs: cmake make libgsl0-dev Repository: https://oncostat.r-universe.dev Date/Publication: 2026-05-06 08:56:07 UTC RemoteUrl: https://github.com/oncostat/surrosurv RemoteRef: HEAD RemoteSha: ae96e92f21a779d3733886a229474daa5d5a06c1 NeedsCompilation: no Packaged: 2026-07-05 05:53:55 UTC; root Author: Federico Rotolo [aut] (ORCID: ), Xavier Paoletti [ctb], Marc Buyse [ctb], Tomasz Burzykowski [ctb], Stefan Michiels [ctb] (ORCID: ), Dan Chaltiel [cre] (ORCID: )